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<i>Morella esculenta<_i> (Buch.-Ham. ex D. Don) I. M. Turner

" in MedChemExpress (MCE) Product Catalog:

56

Inhibitors & Agonists

3

Biochemical Assay Reagents

5

Peptides

3

Inhibitory Antibodies

35

Natural
Products

1

Recombinant Proteins

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N5079
    Lotaustralin

    		Others Others
    Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta .
    Lotaustralin
  • HY-N11484
    5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside

    		Others Others
    5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .
    5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside
  • HY-153151
    Fmoc-DON-Boc

    		Drug Intermediate Cancer
    Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
    Fmoc-DON-Boc
  • HY-N11066
    Anhuienside F

    		Others Others
    Anhuienside F is a natural product that can be isolated from the root of Anemone vitifolia Buch.-Ham .
    Anhuienside F
  • HY-N8111
    Huzhangoside B

    		Others Others
    Huzhangoside B is a Triterpenoids product that can be isolated from the roots of Anemone rivularis Buch.-Ham .
    Huzhangoside B
  • HY-125121
    Esculentoside C

    		Biochemical Assay Reagents Others
    Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta .
    Esculentoside C
  • HY-P5659
    Brevinin-1

    		Bacterial Antibiotic Infection
    Brevinin-1 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
    Brevinin-1
  • HY-P5660
    Brevinin-2

    		Bacterial Infection
    Brevinin-2 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
    Brevinin-2
  • HY-W777107
    1-Oleoyl-2-linoleoyl-rac-glycerol

    DG(18:1/0:0/18:2)

    		 Endogenous Metabolite Others
    1-Oleoyl-2-linoleoyl-rac-glycerol (DG(18:1/0:0/18:2)) is a diacylglycerol, which is composed of a linoleic acid and an oleic acid. 1-Oleoyl-2-linoleoyl-rac-glycerol can be found in dry-cured ham, and acts as the food additive .
    1-Oleoyl-2-linoleoyl-rac-glycerol
  • HY-P5662
    Brevinin-2EC

    		Bacterial Infection
    Brevinin-2EC is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
    Brevinin-2EC
  • HY-P5656
    Brevinin-1Ea

    		Bacterial Infection
    Brevinin-1Ea is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
    Brevinin-1Ea
  • HY-P5658
    Brevinin-1E

    		Bacterial Infection
    Brevinin-1E is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
    Brevinin-1E
  • HY-N1057
    Plantarenaloside

    Yuheinoside

    		 Others Others
    Plantarenaloside is an iridoid glucoside that can be isolated from Leucocarpus perfoliatus G. DON .
    Plantarenaloside
  • HY-N10860
    5-O-beta-D-Glucopyranosylmyricanol

    		Angiotensin Receptor Others
    5-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound isolated from Myrica esculenta that has a weak inhibitory effect on angiotensin-converting enzyme (ACE) .
    5-O-beta-D-Glucopyranosylmyricanol
  • HY-N11678
    Deoxynivalenol-3-β-D-glucoside

    Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside

    		 Drug Metabolite Metabolic Disease
    Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
    Deoxynivalenol-3-β-D-glucoside
  • HY-122218
    JHU-083
    4 Publications Verification

    		 Glutaminase Neurological Disease
    JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
    JHU-083
  • HY-108357
    6-Diazo-5-oxo-L-nor-Leucine
    Maximum Cited Publications
    9 Publications Verification

    L-6-Diazo-5-oxonorleucine; Don

    		 Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
    6-Diazo-5-oxo-L-nor-Leucine
  • HY-N4094
    Morellic acid

    		Others Inflammation/Immunology
    Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
    Morellic acid
  • HY-108357R
    6-Diazo-5-oxo-L-nor-Leucine (Standard)

    L-6-Diazo-5-oxonorleucine (Standard); Don (Standard)

    		 Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-N4094R
    Morellic acid (Standard)

    		Others Inflammation/Immunology
    Morellic acid (Standard) is the analytical standard of Morellic acid. This product is intended for research and analytical applications. Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
    Morellic acid (Standard)
  • HY-167827
    Hsp90-IN-34

    		HSP Cancer
    Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90/Aha1 (KDapp=23.5 µM). Hsp90-IN-34 modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1 .
    Hsp90-IN-34
  • HY-N1271
    Scutellaric acid

    		Others Others
    Scutellaric acid is a Triterpenoids product that can be isolated from the herb of Scutellaria barbata D. Don .
    Scutellaric acid
  • HY-N3371
    Longikaurin E

    (-)-Longikaurin E

    		 Others Others
    Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .
    Longikaurin E
  • HY-N9180
    8α-Methacryloyloxy-13-ethoxyvernojalcanolide

    		Others Others
    8α-Methacryloyloxy-13-ethoxyvernojalcanolide is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia esculenta .
    8α-Methacryloyloxy-13-ethoxyvernojalcanolide
  • HY-N7521
    Procyanidin C2

    Procyanidine C2

    		 Others Others
    Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .
    Procyanidin C2
  • HY-N1270
    Scutebata G

    		Others Others
    Scutebata G is a Diterpenoids product that can be isolated from the herbs of Scutellaria barbata D.Don .
    Scutebata G
  • HY-N3402
    Larixinol

    Abiesinol E; Listvenol

    		 Others Others
    Larixinol (Abiesinol E) is a Diterpenoids product that can be isolated from the herbs of Scutellaria barbata D. Don .
    Larixinol
  • HY-N3067
    Picrasin B acetate

    		Others Others
    Picrasin B acetate is a Diterpenoids product that can be isolated from the herbs of Picrasma quassioides (D. Don) Benn .
    Picrasin B acetate
  • HY-N2726
    6'-O-p-Hydroxybenzoylcatalposide

    		Others Others
    6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .
    6'-O-p-Hydroxybenzoylcatalposide
  • HY-N9494
    6-O-Nicotiylbarbatin C

    		Others Others
    6-O-Nicotiylbarbatin C is a Diterpenoids product that can be isolated from the herbs of Scutellaria barbata D. Don .
    6-O-Nicotiylbarbatin C
  • HY-N6685
    3-Acetyldeoxynivalenol

    		Others Cardiovascular Disease
    3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .
    3-Acetyldeoxynivalenol
  • HY-N3866
    Esculentic acid

    		COX Inflammation/Immunology
    Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta .
    Esculentic acid
  • HY-N1623
    1-Hydroxy-2,3,4,7-tetramethoxyxanthone

    		Endogenous Metabolite Metabolic Disease
    1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .
    1-Hydroxy-2,3,4,7-tetramethoxyxanthone
  • HY-N12838
    Glycerol-2-(3-methoxy-4-hydroxybenzoicacid)ether

    		Others Others
    Glycerol-2-(3-methoxy-4-hydroxybenzoicacid)ether is a phenolic derivative and can be isolated from Picrasma quassioides (D. Don) Benn .
    Glycerol-2-(3-methoxy-4-hydroxybenzoicacid)ether
  • HY-N3706
    Dehydro-α-lapachone

    		Fungal Infection
    Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
    Dehydro-α-lapachone
  • HY-N1390
    Syringaldehyde

    		COX Metabolic Disease Inflammation/Immunology
    Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .
    Syringaldehyde
  • HY-150287
    Insulin-Transferrin-Selenium, 100X
    2 Publications Verification

    ITS-G

    		 Biochemical Assay Reagents Endocrinology
    Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12 . Insulin-Transferrin-Seleniu is added to basal medium to reduce the amount of fetal calf serum required to culture cells.
    Insulin-Transferrin-Selenium, 100X
  • HY-173051
    Antiparasitic agent-24

    		Parasite Infection
    Antiparasitic agent-24 (Compound 14a) is an antiparasitic agent, with EC50s of 0.005 μM (L. maj), 0.069 μM (L. don), 0.82 μM (T. brucei), 4.1 μM (T. cruzi) respectively .
    Antiparasitic agent-24
  • HY-N6685R
    3-Acetyldeoxynivalenol (Standard)

    		Others Cardiovascular Disease
    3-Acetyldeoxynivalenol (Standard) is the analytical standard of 3-Acetyldeoxynivalenol. This product is intended for research and analytical applications. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .
    3-Acetyldeoxynivalenol (Standard)
  • HY-N6685S1
    3-Acetyldeoxynivalenol-13C17

    		Isotope-Labeled Compounds Cardiovascular Disease
    3-Acetyldeoxynivalenol- 13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .
    3-Acetyldeoxynivalenol-13C17
  • HY-N3552
    Catalposide

    		NF-κB Inflammation/Immunology
    Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .
    Catalposide
  • HY-128775
    JHU395

    		Drug Derivative Cancer
    JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
    JHU395
  • HY-N1390R
    Syringaldehyde (Standard)

    		COX Metabolic Disease Inflammation/Immunology
    Syringaldehyde (Standard) is the analytical standard of Syringaldehyde. This product is intended for research and analytical applications. Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .
    Syringaldehyde (Standard)
  • HY-P99029
    Magrolimab
    2 Publications Verification

    Hu5F9-G4

    		 CD47 Cancer
    Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47, thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer .
    Magrolimab
  • HY-N2205
    Esculentoside H
    1 Publications Verification

    		 NF-κB JNK Cancer
    Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .
    Esculentoside H
  • HY-168884
    AV457

    		mTOR Metabolic Disease
    AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT .
    AV457
  • HY-D0854
    Acid Red sodium

    Acid Violet 19; Acid fuchsin sodium

    		 Biochemical Assay Reagents Others
    Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
    Acid Red sodium
  • HY-P99253
    Mogamulizumab

    KW-0761

    		 CCR Inflammation/Immunology Cancer
    Mogamulizumab (KW-0761) is a recombinant anti-CCR4 monoclonal antibody (MAb). Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL) .
    Mogamulizumab
  • HY-N0632
    Esculentoside A
    2 Publications Verification

    		 COX NF-κB Inflammation/Immunology
    Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
    Esculentoside A
  • HY-W099547
    Dihexadecyl hydrogen phosphate

    		Liposome Others
    Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
    Dihexadecyl hydrogen phosphate

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